Ye Mei

Professor of Physics
State Key Laboratory of Precision Spectroscopy 
East China Normal University

Lab Group:
Room A1012, Science Building, East China Normal University, 3663 North Zhongshan Road


B.Sc. Nanjing University 2002; Ph.D. Nanjing University 2007

Areas of Research/Interest

Computational Biophysics and Biochemistry

Research Description

The main research interest in Ye Mei’s group is to develop new methods that can remarkably accelerate the free energy calculations at QM/MM level for organic reactions in condensed phase and enzymatic reactions. The basic ingredient is the reference potential method, in which an auxiliary Hamiltonian is utilized in the exploration of the phase space, and the real Hamiltonian is used for the energy evaluation. With this strategy, the free energy calculations can be enhanced by several orders of magnitude. His group is also interested in force field development for proteins.

Selected Publications