Regulation of Chromosome Segregation and Its Exploitation on Phenotypic Cancer Drug Screen

Topic: 
Regulation of Chromosome Segregation and Its Exploitation on Phenotypic Cancer Drug Screen
Date & Time: 
Wednesday, April 12, 2017 - 16:45 to 17:45
Speaker: 
Jungseog Kang, Assistant Professor of Biology
Location: 
Room 210, NYU Shanghai | 1555 Century Avenue, Pudong New Area, Shanghai

Abstract:

Precise orchestration of chromosome segregation during mitotic cell division is vital to keep genetic stability of eukaryotic cells and mitotic kinases such as cyclin dependent kinase-1, aurora kinases, or spindle assembly checkpoint kinases, play key roles in this process.  Because of their vital roles in mitotic progression, mitotic kinases are often exploited as the chemotherapeutic targets of cancer. In the talk, the principle components of the mitotic machinery and their coordination by spindle assembly checkpoint kinases such as monopolar spindle kinase-1 will be discussed in a molecular detail. Additionally, the conceptual application of a high-content image-based analysis on cancer drug screening, an interdisciplinary study to fight the cancer, will be discussed.


NYU Shanghai STEM seminar series is a weekly seminar series on every Wednesday, starting from 12th October 2016. 
Please see below tentative schedule of STEM seminar series in 2017 Spring Semester.

Location & Details: 

To our visitors

  • RSVP may be required for this event.  Please check event details
  • Visitors will need to present a photo ID at the entrance
  • There is no public parking on campus
  • Entrance only through the South Lobby (1555 Century Avenue) 
  • Taxi card
  • Metro: Century Avenue Station, Metro Lines 2/4/6/9 Exit 6 in location B
  • Bus: Century Avenue at Pudian Road, Bus Lines 169/987