Abstract of the Talk
Our research interests are to: (i) unravel the principles governing biological processes and use them to identify novel drug targets and guide drug design, and (ii) develop new methods for studying macromolecular interactions.
This talk will provide an example of how our studies help to unravel the principles governing the role of Zn in proteins and the reactivity of Zn finger cores and how they guide drug design help to identify novel drug targets.
Carmay Lim obtained her Ph.D. degree in Chemical Physics from the University of Minnesota, Minneapolis in 1984. After carrying out postdoctoral research at AT&T Bell Laboratories, Murray Hill and at Harvard University, she joined the faculties of the Departments of Medical Genetics, Biochemistry, and Chemistry at the University of Toronto. In 1995, she moved to the Institute of Biomedical Sciences, Academia Sinica in Taiwan where she is currently Distinguished Research Fellow. She is also Adjunct Professor at the chemistry department in National Tsing Hua University. Her research interests include (1) unraveling the principles governing biological processes and applying them to guide drug design and identify new drug targets, and (2) developing new computational techniques/algorithms for studying macromolecular interactions. She has received several awards including the National Science Council Outstanding Scientist Award, the Foundation for the Advancement of Outstanding Scholarship Outstanding Scholar Award, and the Ministry of Education Academic Award. She has served on the Editorial Advisory Board of the Journal of American Chemical Society and is currently on the Editorial Advisory Board of several journals including the Journal of Physical Chemistry B and Jornal of Chemical Inoformation and Modeling.